Disease-disease network
Dataset information
This is disease-disease network that contains information on relationships between inherited, developmental, and acquired human diseases. Nodes represent diseases and edges represent associations between them. Associations are recorded from a clinical perspective of location (e.g., brain glioblastoma multiforme is a brain glioma, and brain glioma is a brain cancer) and disease etiology (e.g., Brill-Zinsser disease is a epidemic typhus, and epidemic typhus is a typhus).
| Dataset statistics | |
|---|---|
| Nodes | 6878 |
| Edges | 6877 |
| Nodes in largest SCC | 6878 |
| Fraction of nodes in largest SCC | 1.000000 |
| Edges in largest SCC | 6877 |
| Fraction of edges in largest SCC | 1.000000 |
| Average clustering coefficient | 0.000000 |
| Number of triangles | 42964 |
| Fraction of closed triangles | 0.000000 |
| Diameter (longest shortest path) | 23 |
| 90-percentile effective diameter | 14.515218 |
The information is based on the hierarchical structure of Disease Ontology that defines diseases using universally applicable principles, such as etiology and affected body systems.
References
- Disease Ontology 2015 update: an expanded and updated database of human diseases for linking biomedical knowledge through disease data. Kibbe, Warren A., et al. Nucleic Acids Research. 2014.
- MINER: Gigascale multimodal biological network. Stanford SNAP Group. GitHub Repository. 2017.
Files
| File | Size | Description |
|---|---|---|
| DD-Miner_miner-disease-disease.tsv.gz | 214KB | Disease-disease relationships (diseases are given by DOIDs, i.e., Disease Ontology terms) |