Classification of drug side-effects into categories

Dataset information

This is a list of drug side-effects that provides a high-level classification of side effects into side-effect categories. The categories represent disease classes. Side-effects can be viewed as diseases that occur on top of a primary disease in an individual (primary disease is a medical condition for which a particular drug is prescribed). Side effects can thus be assigned to disease classes based on their etiology and the affected organ systems.

The information on disease classes is extracted from the Disease Ontology.

References

• Modeling polypharmacy side effects with graph convolutional networks. Marinka Zitnik, Monica Agrawal, and Jure Leskovec. Bioinformatics. 2018.
  Presented at ISMB 2018

• Disease Ontology 2015 update: an expanded and updated database of human diseases for linking biomedical knowledge through disease data. Kibbe, Warren A., et al. Nucleic Acids Research. 2014.
  

Files