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Tissue-specific protein-function associations

Dataset information

This is a collection of protein-function association networks for a large number of human tissues. Nodes represent human proteins, tissues, and biological functions. Edges represent associations that indicate different biological roles of proteins in various tissues and cell types.


Dataset statistics
Nodes 2564
Edges 18104
Nodes in largest SCC 2564
Fraction of nodes in largest SCC 1.000000
Edges in largest SCC 18104
Fraction of edges in largest SCC 1.000000
Average clustering coefficient 0.000000
Number of triangles 943127
Fraction of closed triangles 0.000000
Diameter (longest shortest path) 6
90-percentile effective diameter 3.925416
Average tissues per edge 1.138920
Median tissues per edge 1
Standard deviation of tissues per edge 0.370247

The information on biological functions taking place in various tissues is determined based on manual curation and knowledge extracted from a tissue hierarchy. For example, 'low-density lipoprotein particle remodeling' is a biological function specific to blood plasma.

References


Files

File Size Description
TFG-Ohmnet_tissue-function-gene.tsv.gz 539KB Tissue-specific protein-function associations (edgelist)