Classification of cellular functions into a hierarchy
Dataset information
This is a biological function network that classifies biological functions into a hierarchy. The hierarchy is specified by Gene Ontology that describes biological functions and relationships between them. Biological functions capture biological processes (i.e., pathways and larger processes made up of the activities of multiple gene products), cellular components (i.e., components/organelles where gene products are active), and molecular functions (i.e., molecular activities of gene products).
| Dataset statistics | |
|---|---|
| Nodes | 46027 |
| Edges | 106510 |
| Nodes in largest SCC | 46007 |
| Fraction of nodes in largest SCC | 1.000000 |
| Edges in largest SCC | 106499 |
| Fraction of edges in largest SCC | 0.999897 |
| Average clustering coefficient | 0.102073 |
| Number of triangles | 40632618 |
| Fraction of closed triangles | 0.000738 |
| Diameter (longest shortest path) | 16 |
| 90-percentile effective diameter | 8.341534 |
The information is extracted from Gene Ontology, which defines the universe of concepts relating to biological functions, and how these functions are related to each other.
References
- Gene Ontology: tool for the unification of biology. Ashburner, Michael, et al. Nature Genetics. 2000.
- MINER: Gigascale multimodal biological network. Stanford SNAP Group. GitHub Repository. 2017.
Files
| File | Size | Description |
|---|---|---|
| FF-Miner_miner-func-func.tsv.gz | 2.6MB | Function-function network (nodes are Gene Ontology terms) |